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Depression (Major Depressive Disorder)

Depression is a common but serious mood disorder that affects how a person feels, thinks, and functions. It can lead to persistent feelings of sadness, hopelessness, and a loss of interest in activities once enjoyed. These symptoms interfere with daily life—at home, at work, and in relationships.

While it’s normal to feel down at times, depression is different. For those experiencing depression, symptoms are:

  • More intense than typical sadness or grief

  • Long-lasting—typically for two weeks or more

  • Disruptive to everyday functioning

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Signs & Symptoms

 

Depression symptoms vary by individual, but they generally fall into emotional, cognitive, and physical categories. To receive a diagnosis, symptoms must occur most of the day, nearly every day, for at least two weeks.

Physical & Behavioral Symptoms

  • Changes in appetite—overeating or undereating

  • Noticeable weight loss or gain

  • Sleep disturbances—insomnia or excessive sleeping

  • Slowed movements or restlessness

  • Unexplained aches, pains, or chronic fatigue

  • Withdrawing from loved ones or responsibilities

Emotional & Cognitive Symptoms

  • Persistent sadness, emptiness, or hopelessness

  • Loss of interest or pleasure in hobbies, relationships, or social events

  • Feelings of worthlessness, guilt, or shame without clear cause

  • Difficulty concentrating, remembering, or making decisions

  • Feeling overwhelmed, easily discouraged, or mentally fatigued

  • Thoughts of death or suicide

Depression Diagnosis & Risk Factors 

Diagnosis

A licensed clinician—such as a psychiatrist, psychologist, or clinical social worker—makes a depression diagnosis based on:

  • Clinical interviews

  • Symptom history

  • Standardized assessment tools

Diagnosis requires that symptoms cause significant distress or impairment in daily functioning.

Common Risk Factors

  • Family history of depression or mood disorders

  • Major life transitions, trauma, or chronic stress

  • Ongoing medical issues (e.g., chronic pain, diabetes, heart disease)

  • Hormonal changes (e.g., postpartum, menopause, thyroid imbalances)

  • Substance use disorders

  • History of anxiety, PTSD, or other mental health condition

Treatment Options

Depression is treatable, and many people recover with the right support. A comprehensive treatment plan often includes a combination of therapy, medication, and lifestyle interventions.

Psychotherapy

  • Cognitive Behavioral Therapy (CBT): Identifies and reshapes negative thought patterns

  • Interpersonal Therapy (IPT): Focuses on improving communication and relationship dynamics

  • Mindfulness-Based Therapy: Encourages self-awareness and emotional regulation

  • Trauma-Informed Therapy: Helps address past trauma contributing to current symptoms

Medication

  • Antidepressants (SSRIs, SNRIs): Adjust brain chemicals like serotonin and norepinephrine

  • Atypical Antidepressants / Mood Stabilizers: Used when traditional options aren't effective

  • Ongoing Monitoring: Effects may take several weeks—collaboration with a prescribing provider is essential

Holistic & Lifestyle Approaches

  • Exercise & Movement: Enhances mood and energy

  • Nutrition: Diets rich in omega-3s, vitamins, and fiber support brain health

  • Sleep Hygiene: Consistent sleep routines can stabilize mood

  • Supplements (with medical guidance): B12, D, magnesium may help in some cases

  • Complementary Therapies: Acupuncture, massage, and yoga can ease physical tension and promote emotional balance

Remember: You’re not alone. With the right care, support, and treatment, healing from depression is possible.

Adult with ADHD receiving holistic therapy and mindfulness coaching

© 2025 Psychiatric Holistic Health. All rights reserved.

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